Informazione e Confronto per Educatori
§ 1 – Incremento ponderale DIETE Si tratta di un effetto collaterale del trattamento con clozapina altrettanto frequente come con i neurolettici classici (Cohen e Coll, 1990; Lieberman e Coll, 1989; Povlsen e Coll, 1985; Schmauss e Coll, 1989). La sua incidenza è variabile ed è correlata alla durata del trattamento (Cohen e Coll, 1990; Honigfeld e Patin, 1990).
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Honigfeld G, Patin J. A two year clinical and economic follow-up of patients on clozapine. Hosp Community Psychiat 1990; 41: 882-885.
Kamran A, Doraiswamy PM, Jane JL, Hammet EB, Dunn L. Severe hyperglycemia associated with high doses of clozapine.Am J Psychiatry 1994; 151: 1395.
Kane JM, Cooper TB, Sacher EJ, Halpern FS, Bailine S. Clozapine: plasma levels and clozapine response.Psychopharmacology 1981; 73: 184-187.
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Meltzer HY. Clinical studies on the mechanism of action of clozapine: the dopamine-serotonine hypotesis of schizophrenia.Psychopharmacology (Berlin) 1989; 99(Suppl): S18-S27.
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